Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Streamlined, PCR-based testing for pfhrp2- and pfhrp3-negative Plasmodium falciparum

2 Apr 2018

Abstract excerpt

BACKGROUND: Rapid diagnostic tests (RDTs) that detect histidine-rich protein 2 (PfHRP2) are used throughout Africa for the diagnosis of Plasmodium falciparum malaria. However, recent reports indicate that parasites lacking the pfhrp2 and/or histidine-rich protein 3 (pfhrp3) genes, which produce antigens detected by these RDTs, are common in select regions of South America, Asia, and Africa. Proving the absence of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Malaria Research and Control
Share to vaccines and immunoinformatics approaches
Share to Vector-borne infectious diseases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 29609602
DOI: 10.1186/s12936-018-2287-4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Streamlined, PCR-based testing for pfhrp2- and pfhrp3-negative Plasmodium falciparumPMID 29609602Read ↗

A novel multiplex qPCR assay for detection of Plasmodium falciparum with histidine-rich protein 2 and 3 (pfhrp2 and pfhrp3) deletions in polyclonal infectionsSemantic proximity Read ↗

A multiplex qPCR approach for detection of pfhrp2 and pfhrp3 gene deletions in multiple strain infections of Plasmodium falciparumSemantic proximity Read ↗

Causes of false-negative rapid diagnostic tests for symptomatic malaria in the DRCSemantic proximity Read ↗

Analysis of false-negative rapid diagnostic tests for symptomatic malaria in the Democratic Republic of the CongoSemantic proximity Read ↗

Deletions of pfhrp2 and pfhrp3 genes were uncommon in rapid diagnostic test-negative Plasmodium falciparum isolates from UgandaSemantic proximity Read ↗

pfhrp2 and pfhrp3 Gene Deletions That Affect Malaria Rapid Diagnostic Tests for Plasmodium falciparum: Analysis of Archived Blood Samples From 3 African Countries.Semantic proximity Read ↗

Community-based surveys for Plasmodium falciparum pfhrp2 and pfhrp3 gene deletions in selected regions of mainland TanzaniaSemantic proximity Read ↗

A Novel Multiplex qPCR Assay for Detection of <i>Plasmodium falciparum</i> with <i>Histidine-rich Protein 2 and 3 (pfhrp2 and pfhrp3)</i> Deletions in Polyclonal InfectionsSemantic proximity Read ↗

Molecular surveillance of pfhrp2 and pfhrp3 deletions in Plasmodium falciparum isolates from MozambiqueSemantic proximity Read ↗

Plasmodium falciparum pfhrp2 and pfhrp3 gene deletions among patients in the DRC enrolled from 2017 to 2018Semantic proximity Read ↗

Low Prevalence of Plasmodium falciparum Histidine-Rich Protein 2 and 3 Gene Deletions—A Multiregional Study in Central and West AfricaSemantic proximity Read ↗

Plasmodium falciparum parasites with histidine-rich protein 2 (pfhrp2) and pfhrp3 gene deletions in two endemic regions of KenyaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.