Article

Molecular analysis of DNA damage induced by a novel trinuclear platinum complex (BBR 3464)

2001-01-01

Abstract excerpt

We evaluated the activity of the trinuclear platinum complex BBR 3464 in two human ovarian carcinoma cell lines (OAW42, A2780) and in their cisplatin-resistant counterparts (OAW42Mer, A2780cp8). An increased cytotoxic potency of BBR 3464 compared to cisplatin was generally observed, an a collateral sensitivity or a very modest cross-resistance to BBR 3464 was found in OAW42Mer and A2780cp8 cell lines, respectively...

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Identifiers and source

Literature Corpus work: 2755889b-c9c2-5a03-ba7b-78e7af896cca
DOI: 10.21954/ou.ro.0000f9b7

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