Article

Accelerated human liver progenitor generation from pluripotent stem cells by inhibiting formation of unwanted lineages

2017-08-10

Abstract excerpt

Despite decisive progress in differentiating pluripotent stem cells (PSCs) into diverse cell-types, the often-lengthy differentiation and functional immaturity of such cell-types remain pertinent issues. Here we address the first challenge of prolonged differentiation in the generation of hepatocyte-like cells from PSCs. We delineate a roadmap describing the extracellular signals controlling six sequential branchi...

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Literature Corpus work: 27188549-3321-5b2a-ac45-518789646bcb
DOI: 10.1101/174698

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