Article
The Use of Human Pluripotent Stem Cells for Modeling Liver Development and Disease
25 Sept 2018
Abstract excerpt
The use of pluripotent stem cells (PSCs) has transformed the investigation of liver development and disease. Clinical observations and animal models have provided the foundations of our understanding in these fields. While animal models remain essential research tools, long experimental lead times and low throughput limit the scope of investigations. The ability of PSCs to produce large numbers of human...
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