Article

A novel GATA-binding protein 4 gene variation associated with familial atrial septal defect

2018-03-06

Abstract excerpt

Atrial septal defect (ASD) is the most common congenital heart defect. Part of ASD exhibits familial predisposition, but the genetic mechanism remains largely unknown. In the current study, we use multiple methods to identify and confirm the gene associated with a familial ASD. Chromosomal microarray analyses, whole exome sequencing, Sanger sequencing, multiple bioinformatics programs, in silico protein structure...

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Literature Corpus work: 26b4527b-0c9a-5298-88d2-ac27d75e492b
DOI: 10.1101/277780

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