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Article

c.620C>T mutation in GATA4 is associated with congenital heart disease in South India.

BMC medical genetics - 18 Feb 2015

Mattapally Saidulu, Nizamuddin Sheikh, Murthy Kona Samba, Thangaraj Kumarasamy, Banerjee Sanjay K

Abstract excerpt

BACKGROUND: Congenital heart diseases (CHDs) usually refer to abnormalities in the structure and/or function of the heart that arise before birth. GATA4 plays an important role in embryonic heart development, hence the aim of this study was to find the association of GATA4 mutations with CHD among the south Indian CHD patients. METHOD: GATA4 gene was sequenced in 100 CHD patients (ASD, VSD, TOF and SV) and 200...

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Identifiers

PMID: 25928801
DOI: 10.1186/s12881-015-0152-7
PMCID: PMC4422155

Genes

GATA4

Variants

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