Article
Glioblastoma invasion is controlled by parkin via a presenilin-dependent transcriptional control of N-cadherin
2025-11-04
Abstract excerpt
<title>Abstract</title> <p>Glioblastoma (GBM) is a highly invasive uncurable cancer characterized by a poor prognosis. Parkin is a E3-ligase and transcription factor protein that has emerged as a tumor suppressor in various cancers including GBM via control of proliferation, cell metabolism and invasion. However, the contribution of its ligase and transcription factor function in invasion remained unknown. We exa...
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Identifiers and source
- Literature Corpus work
- 26b17431-5e32-5bb8-b3a5-a33e5c1e99bc
- DOI
- 10.21203/rs.3.rs-7481736/v1