Article

Caenorhabditis Elegans NHR-14/HNF4α Cooperates with cep-1/ p53 to Regulate DNA Damage-induced Apoptosis

2022-01-17

Abstract excerpt

<title>Abstract</title> <p><bold>Background</bold>: Nuclear hormone receptor is involved in transcriptional regulation and many important cellular processes including development and metabolism. However, its role in DNA damage-induced apoptosis remains elusive.<bold>Methods</bold>: Synchronized young adult animals were irradiated with different doses of gamma-Ray, and then put back to culture at 20 <sup>0</sup> C...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 26575c49-02a3-5d3d-8c58-305c57c63a9d
DOI: 10.21203/rs.3.rs-1231254/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Caenorhabditis Elegans NHR-14/HNF4α Cooperates with cep-1/ p53 to Regulate DNA Damage-induced ApoptosisDOI 10.21203/rs.3.rs-1231254/v1Read

Fertility and Germline Stem Cell Maintenance under Different Diets Requires nhr-114/HNF4 in C. elegansSemantic proximity Read

Genetic and cellular sensitivity of <i>Caenorhabditis elegans</i> to the chemotherapeutic agent cisplatinSemantic proximity Read

The Caenorhabditis elegans HP1 family protein HPL-2 maintains ER homeostasis through the UPR and hormesis.Semantic proximity Read

Nuclear hormone receptor NHR-49 is an essential regulator of stress resilience and healthy aging in Caenorhabditis elegansSemantic proximity Read

The Caenorhabditis elegans orphan nuclear hormone receptor gene nhr-2 functions in early embryonic development.Semantic proximity Read

Repression of a potassium channel by nuclear hormone receptor and TGF-β signaling modulates insulin signaling in Caenorhabditis elegans.Semantic proximity Read

The nucleotide excision repair pathway is required for UV-C-induced apoptosis in Caenorhabditis elegans.Semantic proximity Read

The nuclear receptor gene nhr-25 plays multiple roles in the Caenorhabditis elegans heterochronic gene network to control the larva-to-adult transition.Semantic proximity Read

The SCF FSN-1 ubiquitin ligase controls germline apoptosis through CEP-1/p53 in C. elegans.Semantic proximity Read

The Caenorhabditis elegans nuclear receptor gene nhr-25 regulates epidermal cell development.Semantic proximity Read

Nuclear hormone receptor regulation of microRNAs controls developmental progression.Semantic proximity Read

nhr-25, the Caenorhabditis elegans ortholog of ftz-f1, is required for epidermal and somatic gonad development.Semantic proximity Read