Article

Inhibition of Stromal Biglycan Promotes Normalization of the Tumor Microenvironment and Enhances Chemotherapeutic Efficacy

2021-01-13

Abstract excerpt

<title>Abstract</title> <p>BackgroundBiglycan is a proteoglycan found in the extracellular matrix. We have previously shown that biglycan is secreted from tumor endothelial cells and induces tumor angiogenesis and metastasis. However, the function of stroma biglycan in breast cancer is still unclear. MethodsBiglycan gene analysis and its prognostic values in human breast cancers were based on TCGA data. E0771 bre...

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Literature Corpus work: 265146af-c051-512b-a83d-eb04f44565e6
DOI: 10.21203/rs.3.rs-142861/v1

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