Article

Analysis of Divergent Gene Expression between HPV+ and HPV- Head and Neck Squamous Cell Carcinoma Patients

2025-04-18

Abstract excerpt

Human Papillomavirus (HPV) is a non-enveloped virus with a circular double-stranded DNA genome. It is one of the most common sexually transmitted infections, with high-risk types such as HPV-16 and HPV-18 linked to anogenital and head and neck squamous cell carcinomas (HNSCC). HNSCC includes cancers of the oral cavity, pharynx, larynx, and related regions, caused by carcinogens or persistent viral infections. HPV-...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 26329b75-584e-5929-9b7b-b8db42f44a29
DOI: 10.1101/2025.04.14.648798

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Analysis of Divergent Gene Expression between HPV+ and HPV- Head and Neck Squamous Cell Carcinoma PatientsDOI 10.1101/2025.04.14.648798Read

Subtypes of HPV-Positive Head and Neck Cancers Are Associated with HPV Characteristics, Copy Number Alterations, PIK3CA Mutation, and Pathway Signatures.Semantic proximity Read

Integrative Analysis of Head and Neck Cancer Identifies Two Biologically Distinct HPV and Three Non-HPV SubtypesSemantic proximity Read

Molecular Tumor Subtypes of HPV-Positive Head and Neck Cancers: Biological Characteristics and Implications for Clinical OutcomesSemantic proximity Read

Molecular Tumor Subtypes of HPV-Positive Head and Neck Cancers: Biological Characteristics and Implications for Clinical OutcomesSemantic proximity Read

Gene expression profiles in HPV‐infected head and neck cancerSemantic proximity Read

Gene Expression Differences Associated with Human Papillomavirus Status in Head and Neck Squamous Cell CarcinomaSemantic proximity Read

Distinct co-expression networks using multi-omic data reveal novel interventional targets in HPV-positive and negative head-and-neck squamous cell cancerSemantic proximity Read

Novel insights into head and neck cancer using next-generation "omic" technologies.Semantic proximity Read

Histoepigenetic analysis of HPV- and tobacco-associated head and neck cancer identifies both subtype-specific and common therapeutic targets despite divergent microenvironmentsSemantic proximity Read

Distinct co-expression networks using multi-omic data reveal novel interventional targets in HPV-positive and negative head-and-neck squamous cell cancerSemantic proximity Read

Tumor Subtype Classification Tool for HPV-associated Head and Neck CancersSemantic proximity Read

Human Papillomavirus Drives Tumor Development Throughout the Head and Neck: Improved Prognosis Is Associated With an Immune Response Largely Restricted to the OropharynxSemantic proximity Read