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A Nonsteroidal Anti-inflammatory Drug, Zaltoprofen, Inhibits the Growth of Extraskeletal Chondrosarcoma Cells by Inducing PPARγ, p21, p27, and p53

2021-05-05

Abstract excerpt

There is no effective treatment except surgical resection for extraskeletal myxoid chondrosarcoma (EMC). Peroxisome proliferator-activated receptor gamma (PPARγ) is a nuclear receptor and a master transcription factor of adipogenesis-related genes and has been reported as an antitumor target for chondrosarcomas. Herein, we show that a nonsteroidal anti-inflammatory drug, zaltoprofen, induces the expression of PPAR...

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Literature Corpus work
26144428-9f1f-5178-83e4-153d51cb62f0
DOI
10.21203/rs.3.rs-469815/v1
Open publication

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A Nonsteroidal Anti-inflammatory Drug, Zaltoprofen, Inhibits the Growth of Extraskeletal Chondrosarcoma Cells by Inducing PPARγ, p21, p27, and p53DOI 10.21203/rs.3.rs-469815/v1
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