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The benefits of combining an immunomodulator with a chemotherapy agent in chondrosarcoma : a proof of concept with mifamurtide

2025-07-27

Abstract excerpt

<title>Abstract</title> <p>Tumor-associated macrophages (TAMs) play a critical role in the progression of various cancers, including chondrosarcoma, where they can constitute up to 50% of the tumor mass. In chondrosarcoma, TAMs are predominantly of the M2-like phenotype and are linked to more invasive and higher-grade disease. Despite the challenge of chondrosarcoma’s chemo- and radio-resistance due to its slow c...

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Literature Corpus work
36d73f9e-5863-5f02-9f68-75eef2da10e3
DOI
10.21203/rs.3.rs-6954396/v1
Open publication

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The benefits of combining an immunomodulator with a chemotherapy agent in chondrosarcoma : a proof of concept with mifamurtideDOI 10.21203/rs.3.rs-6954396/v1
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