Article

Charting Brain Structure in 22q11.2 Deletion Syndrome with Clinical Neuroimaging

2025-11-27

Abstract excerpt

<h4>Background</h4> 22q11.2 deletion syndrome (22q11DS) is a common microdeletion associated with widespread brain alterations and elevated risk for schizophrenia and other neuropsychiatric conditions. Prospective research studies often exclude individuals with severe cognitive impairment, medical comorbidities, or inability to tolerate research MRI without sedation, features common in 22q11DS. This limits both t...

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Literature Corpus work: 260785c5-9a1c-51c2-9915-9cd99910ecaa
DOI: 10.1101/2025.11.25.25339898

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