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Altered cortical thickness development in 22q11.2 deletion syndrome and association with psychotic symptoms

12 Jul 2021

Abstract excerpt

Schizophrenia has been extensively associated with reduced cortical thickness (CT), and its neurodevelopmental origin is increasingly acknowledged. However, the exact timing and extent of alterations occurring in preclinical phases remain unclear. With a high prevalence of psychosis, 22q11.2 deletion syndrome (22q11DS) is a neurogenetic disorder that represents a unique opportunity to examine brain maturation in...

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PMID: 34253864
DOI: 10.1038/s41380-021-01209-8

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