Article

Convergent and Divergent Cerebellar Alterations in 22q11.2 Copy Number Variants

2025-10-08

Abstract excerpt

<h4>Background</h4> Individuals with copy number variants (CNVs) at 22q11.2 are at elevated risk for neurodevelopmental and psychiatric disorders, including autism spectrum disorder and intellectual disability. For psychosis, effects diverge, with 22q11.2 deletion (22qDel) conferring one of the highest known risks for schizophrenia, while duplication (22qDup) may be protective. Prior investigations of neurobiolog...

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Literature Corpus work: dd5242f4-9841-551d-bc00-0e631d14370e
DOI: 10.1101/2025.10.07.679846

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