Back to search

Article

Identification of GATA2-AS1- hsa-miR-125b-5p-PLAU ceRNA regulatory network as novel biomarkers for prethrombotic state in patients with coronary artery disease

2026-01-29

Abstract excerpt

<title>Abstract</title> <p>Current diagnostic tools lack specificity for identifying the prethrombotic state (PTS), a critical precursor to coronary thrombosis in coronary artery disease (CAD). This study aimed to discover and validate specific multi-omics biomarkers for PTS detection to enable early intervention. Integrated transcriptomic and proteomic analyses were performed on peripheral blood mononuclear cell...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
25a03930-2f7f-5cb8-8737-c186b864e61f
DOI
10.21203/rs.3.rs-7671890/v1
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Identification of GATA2-AS1- hsa-miR-125b-5p-PLAU ceRNA regulatory network as novel biomarkers for prethrombotic state in patients with coronary artery diseaseDOI 10.21203/rs.3.rs-7671890/v1
Coordinated suppression of lectin complement pathway effectors and upregulation of SERPING1 defines a thrombo-inflammatory regulatory signature in cardiovascular diseaseSemantic proximity
Multi-omics and network propagation reveal latent innate immune programmes stratifying high-risk thrombotic primary antiphospholipid syndromeSemantic proximity
Screening of lncRNA‐miRNA‐mRNA Coexpression Regulatory Networks Involved in Acute Traumatic Coagulation Dysfunction Based on CTD, GeneCards, and PharmGKB DatabasesSemantic proximity
Identification of Key Genes as Early Warning Signals of Acute Myocardial Infarction Based on Weighted Gene Correlation Network Analysis and Dynamic Network Biomarker AlgorithmSemantic proximity
Analysis and Regulatory Mechanisms of Platelet-related Genes in Patients with Ischemic StrokeSemantic proximity
Molecular Pathophysiology of Cardiac Injury and Cardiac Microthrombi in Fatal COVID-19: Insights from Clinico-histopathologic and Single Nuclei RNA Sequencing AnalysesSemantic proximity
The underlying molecular mechanisms and biomarkers of Hip fracture combined with deep vein thrombosis based on self sequencing bioinformatics analysisSemantic proximity
The diagnostic value of hyperlipidemia and lipophagy-related genes, PLAUR, IVNS1ABP, and QKI, in acute myocardial infarctionSemantic proximity
Competing endogenous RNA expression profiling in pre-eclampsia identifies hsa_circ_0036877 as a potential novel blood biomarker for early pre-eclampsiaSemantic proximity
Genetic assessment of efficacy and safety profiles of coagulation cascade proteins identifies Factors II and XI as actionable anticoagulant targetsSemantic proximity
Identification of key genes and regulatory networks associated with atherosclerotic carotid artery stenosis through comprehensive bioinformatics analysis and machine learningSemantic proximity
Determining Potential Therapeutic Targets for Venous Thrombosis through Network Pharmacology, Cluster Typing, WGCNA, Machine Learning, Immune Infiltration Analysis, and ceRNA NetworksSemantic proximity
Select a neighboring publication to make it the new centre.