Article
Identification of key genes and regulatory networks associated with atherosclerotic carotid artery stenosis through comprehensive bioinformatics analysis and machine learning
2025-08-11
Abstract excerpt
<title>Abstract</title> <p> <bold>Objective:</bold> A comprehensive bioinformatics analysis was conducted to identify key genes and regulatory networks associated with atherosclerotic carotid artery stenosis (ACAS). <bold>Methods:</bold> Four datasets, including GSE43292, GSE100927, GSE28829, and GSE198600, were integrated to form the training set, with the GSE163154 dataset serving as the validation set. Sub...
Topics
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- Adipokines, Inflammation, and Metabolic Diseases
- Atherosclerosis and Cardiovascular Diseases
- Cancer-related molecular mechanisms research
- Cholesterol and Lipid Metabolism
- Ferroptosis and cancer prognosis
- Galectins and Cancer Biology
- Neurological Disease Mechanisms and Treatments
- Single-cell and spatial transcriptomics
Identifiers and source
- Literature Corpus work
- 81dd251a-a919-5376-a4e7-90c9accbb2cb
- DOI
- 10.21203/rs.3.rs-7112702/v1
