Article

Normal and cancer tissues are accurately characterised by intergenic transcription at RNA polymerase 2 binding sites

2023-03-25

Abstract excerpt

Intergenic transcription in normal and cancerous tissue is pervasive and incompletely understood. To investigate this activity at a global level, we constructed an atlas of over 180,000 consensus RNA Polymerase II (RNAP2) bound intergenic regions from more than 900 RNAP2 ChIP-seq experiments across normal and cancer samples. Using unsupervised analysis, we identified 51 RNAP2 consensus clusters, many of which map...

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Identifiers and source

Literature Corpus work: 25852da2-24b0-5347-babc-41c870401660
DOI: 10.1101/2023.03.24.534112

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