Article

Human Alpha 1 Antitrypsin Suppresses NF-ĸB Activity and Extends Lifespan in Adult Drosophila

2022-08-04

Abstract excerpt

<title>Abstract</title> <p>Human alpha 1 antitrypsin (hAAT) is a multifunctional protein, which has been shown to have anti-inflammatory and cellular protective properties. While previous studies demonstrated the antiaging potential of hAAT, the mechanism(s) underlying the antiaging effect remain elusive. In this study, we performed a detailed analysis of transcriptomic data, which indicated that NF-ĸB-targeted g...

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Literature Corpus work: 254dfb8e-b747-5d1c-80ea-7784db81c904
DOI: 10.21203/rs.3.rs-1917871/v1

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