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Molecular targets and strategies in the development of nucleic acid cancer vaccines: from shared to personalized antigens

9 Oct 2024

Abstract excerpt

Recent breakthroughs in cancer immunotherapies have emphasized the importance of harnessing the immune system for treating cancer. Vaccines, which have traditionally been used to promote protective immunity against pathogens, are now being explored as a method to target cancer neoantigens. Over the past few years, extensive preclinical research and more than a hundred clinical trials have been dedicated to...

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PMID: 39379923
DOI: 10.1186/s12929-024-01082-x

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