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Genomic diversity and<i>BCL9L</i>mutational status in CTC pools predict overall survival in metastatic colorectal cancer

2025-01-01

Abstract excerpt

The genomic diversity of circulating tumor cells (CTCs) and its clinical implications remain poorly understood. In this study, we characterized the mutational landscape of CTC pools stemming from 29 metastatic colorectal cancer (mCRC) patients and examined its relationship with disease progression. Our analysis revealed substantial variation in mutational burden among patients, with all CTC pools harboring non-sil...

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Literature Corpus work
251583bc-6af4-598d-8b14-5d3bb3f0fb96
DOI
10.1101/2024.12.26.24319649
Open publication

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Genomic diversity and<i>BCL9L</i>mutational status in CTC pools predict overall survival in metastatic colorectal cancerDOI 10.1101/2024.12.26.24319649
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