Article

Therapeutic-scale CAR-NK microrobots with programmable swarm navigation for targeted solid tumour therapy

2025-12-04

Abstract excerpt

<title>Abstract</title> <p> An urgent requirement in chimeric antigen receptor immune cell therapy (e.g., CAR-NK cells) for solid tumours is to engineer the cells for precise tumour targeting. Meanwhile, medical microrobots can be navigated toward specific target sites using external magnetic fields. Here, by bridging these approaches, we turn CAR-NK cells into magnetic biohybrid microrobots (CAR-NK microrobots)...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 24e62a55-d4c5-534e-b4fb-5bbdc8f84433
DOI: 10.21203/rs.3.rs-8166028/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Therapeutic-scale CAR-NK microrobots with programmable swarm navigation for targeted solid tumour therapyDOI 10.21203/rs.3.rs-8166028/v1Read

Remotely Guided Immunobots Engaged in Anti-Tumorigenic Phenotypes for Targeted Cancer Immunotherapy.Semantic proximity Read

Swarming magnetic surface microrollers enable directed locomotion in circular confinementsSemantic proximity Read

Generation of magnetic biohybrid microrobots based on MSC.sTRAIL for targeted stem cell delivery and treatment of cancerSemantic proximity Read

Synthetic Viscoelastic Activating Cells for T Cell Engineering and Cancer TherapySemantic proximity Read

Personalized Drug Delivery with Smart Nanotechnology and AI InnovationsSemantic proximity Read

A Detachable Magnetic Nanodevice for the Efficient Capture and Subtype Identification of Circulating Tumor CellsSemantic proximity Read

Ferrimagnetic Vortex Nanorings Facilitate Efficient and Safe Deep-Brain Magnetothermal Stimulation in Freely Moving MiceSemantic proximity Read

Quantitative Magnetic Deflection Enables Continuous‐Flow Separation of Cell SubtypesSemantic proximity Read

Scale-out production of extracellular vesicles derived from natural killer cells via mechanical stimulation in a seesaw-motion bioreactor for cancer therapySemantic proximity Read

Acoustic Remote Control of Bacterial ImmunotherapySemantic proximity Read

Isosceles Trapezoidal Spiral Microchannel for Separation of Large particles and Giant Cancer cellsSemantic proximity Read

Wake-riding effect-inspired opto-hydrodynamic diatombot for non-invasive trapping and removal of nano-biothreatsSemantic proximity Read