Article

Rescue of SARS-CoV-2 from a single bacterial artificial chromosome

2020-07-22

Abstract excerpt

<h4>ABSTRACT</h4> An infectious coronavirus disease 2019 (COVID-19) emerged in the city of Wuhan (China) in December 2019, causing a pandemic that has dramatically impacted public health and socioeconomic activities worldwide. A previously unknown coronavirus, Severe Acute Respiratory Syndrome CoV-2 (SARS-CoV-2), has been identified as the causative agent of COVID-19. To date, there are no United States (US) Food...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 24a61949-13a0-523f-921b-3281cbb9e8f6
DOI: 10.1101/2020.07.22.216358

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Rescue of SARS-CoV-2 from a single bacterial artificial chromosomeDOI 10.1101/2020.07.22.216358Read

Rescue of SARS-CoV-2 from a Single Bacterial Artificial ChromosomeSemantic proximity Read

Generation of Recombinant SARS‐CoV‐2 Using a Bacterial Artificial ChromosomeSemantic proximity Read

Use of a Bacterial Artificial Chromosome to Generate Recombinant SARS-CoV-2 Expressing Robust Levels of Reporter GenesSemantic proximity Read

Using a reverse genetics system to generate recombinant SARS-CoV-2 expressing robust levels of reporter genesSemantic proximity Read

Cloning of a Passage-Free SARS-CoV-2 Genome and Mutagenesis Using Red RecombinationSemantic proximity Read

Scarless SARS-CoV-2 Genome Engineering and Variant AnalysisSemantic proximity Read

Versatile SARS-CoV-2 Reverse-Genetics Systems for the Study of Antiviral Resistance and ReplicationSemantic proximity Read

A plasmid DNA-launched SARS-CoV-2 reverse genetics system and coronavirus toolkit for COVID-19 researchSemantic proximity Read

Establishment of a Reverse Genetics System for SARS-CoV-2 Using Circular Polymerase Extension ReactionSemantic proximity Read

Reverse genetics systems for SARS‐CoV‐2Semantic proximity Read

Subgenomic SARS-CoV-2 replicon and reporter replicon cell lines enable ultrahigh throughput antiviral screening and mechanistic studies with antivirals, viral mutations or host factors that affect COVID-19 replicationSemantic proximity Read

A novel cell culture system modeling the SARS-CoV-2 life cycleSemantic proximity Read