Article

Syntenic lncRNAs exhibit DNA regulatory functions with sequence evolution

2024-04-26

Abstract excerpt

Syntenic long non-coding RNAs (lncRNAs) often show limited sequence conservation across species, prompting concern in the field. This study delves into functional signatures of syntenic lncRNAs between humans and zebrafish. Syntenic lncRNAs have high expression in zebrafish and ∼90% near protein-coding genes in sense or antisense orientation. During early zebrafish development and human embryonic stem cells (H1-hE...

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Literature Corpus work: 2469ceb8-1c6d-5b21-80df-a2b56bfa578f
DOI: 10.1101/2024.04.26.588027

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