Article

The reciprocal regulation between mitochondrial-associated membranes and Notch signaling in skeletal muscle atrophy

2023-07-20

Abstract excerpt

Skeletal muscle atrophy and the inhibition of muscle regeneration are known to occur as a natural consequence of aging, yet the underlying mechanisms that lead to these processes in atrophic myofibers remain largely unclear. Our research has revealed that the maintenance of proper mitochondrial-associated endoplasmic reticulum membranes (MAM) is vital for preventing skeletal muscle atrophy in microgravity environm...

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Literature Corpus work: 2449a53f-9b1e-5659-bbde-e66b0504e083
DOI: 10.1101/2023.07.19.549786

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