Article

Defined human PSC culture conditions robustly maintain human PSC pluripotency through Ca <sup>2+</sup> signaling

2023-08-09

Abstract excerpt

<h4>Summary</h4> Human pluripotent stem cells (hPSCs) have significant potential for disease modeling and cell therapies. However, their clinical applicability is limited due to the need for undefined conditions for PSC cultivation, which increase the risk of immunogenicity, result in batch-to-batch variability and finite scalability. These limitations may be circumvented by xeno-free, defined culture conditions....

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Literature Corpus work: 23f32449-140c-583b-b330-115043cb07f2
DOI: 10.1101/2023.08.08.552440

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