Article
Methodology for generating chorioallantoic membrane patient-derived xenograft (CAM-PDX) models of pleural mesothelioma and performing preclinical imaging for the translation of cancer studies and drug screening.
2025-08-14
Abstract excerpt
Background Pleural mesothelioma is a cancer of the lung lining associated with asbestos exposure. Platinum/pemetrexed chemotherapy has been used for many years but provides little benefit and, despite recent immunotherapy advances, prognosis remains poor underpinning the need for development of novel therapeutics or drug repurposing. Fertilized hens’ eggs provide a rapid and cost-effective alternative to murine mo...
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Identifiers and source
- Literature Corpus work
- 23e8cfdb-80f9-5bbb-8fbc-c52a568b7b59
- DOI
- 10.12688/f1000research.163596.2