Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Bioinformatics analysis of gene expression profile in callus tissues of osteoporotic phenotype mice induced by osteoblast-specific Krm2 overexpression.

International journal of rheumatic diseases - 1 Dec 2016

Wang Chengxue, Yu Tiecheng, Tan Lei, Cheng Jieping

Abstract excerpt

PURPOSE: The aim of this study was to explore the molecular mechanism of fracture healing in osteoporotic mice. METHODS: The gene expression profiles of callus tissues of osteoporotic mice and controls were obtained from Gene Expression Omnibus database. The differentially expressed genes (DEGs) and their related biological function and pathways were investigated. In addition, the protein-protein interaction...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Collagen Type I
Share to Collagen Type I, alpha 1 Chain

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Databases, Genetic

Share to Extracellular Matrix

Share to Osteoporosis

Share to Osteoporotic Fractures

Share to Protein Interaction Maps

Share to Up-Regulation

Source

Identifiers

PMID: 26929007
DOI: 10.1111/1756-185X.12840

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Bioinformatics analysis of gene expression profile in callus tissues of osteoporotic phenotype mice induced by osteoblast-specific Krm2 overexpression.PMID 26929007Read ↗

Potential genes and pathways associated with heterotopic ossification derived from analyses of gene expression profilesSemantic proximity Read ↗

A gene co-expression network-based analysis of mesenchymal stromal cells reveals novel genes and molecular pathways underlying heterotopic ossificationSemantic proximity Read ↗

Identification of Transcriptional Factors and Key Genes in Primary Osteoporosis by DNA MicroarraySemantic proximity Read ↗

Analysis of Differentially Expressed Genes in Osteonecrosis of Femoral Head, Osteoarthritis, and Rheumatoid Arthritis by Integrated Microarray AnalysisSemantic proximity Read ↗

Osteoking Promotes Bone Formation and Bone Defect Repair through ZBP1-STAT1-PKR-MLKL-mediated NecroptosisSemantic proximity Read ↗

Identification of Hub Genes and Pathways Associated with Oxidative Stress of Cartilage in Osteonecrosis of Femoral Head Using Bioinformatics AnalysisSemantic proximity Read ↗

Integrated Analysis of Hub Genes and miRNAs in OsteoporosisSemantic proximity Read ↗

Network Pharmacology and Molecular Docking Elucidate the Pharmacological Mechanism of the OSTEOWONDER Capsule for Treating OsteoporosisSemantic proximity Read ↗

Clinical significance linked to functional defects in bone morphogenetic protein type 2 receptor, BMPR2.Semantic proximity Read ↗

Analysis and Validation of Hub Genes in Blood Monocytes of Postmenopausal Osteoporosis PatientsSemantic proximity Read ↗

The intracellular NADH level regulates atrophic nonunion pathogenesis through the CtBP2-p300-Runx2 transcriptional complexSemantic proximity Read ↗

Unveiling the transcriptomic landscape and the potential antagonist feedback mechanisms of TGF-β superfamily signaling module in bone and osteoporosisSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.