Article

Positive selection in the Ebola virus proteome

2019-02-21

Abstract excerpt

To gain insight into the recent evolution of EBOLA virus (EBOV) proteins and identify evolutionary hotspots, I investigated patterns of amino acid substitutions in the proteomes of 49 members of EBOV genus including EBOV, Bundibugyo virus (BDBV), Reston virus (RESTV), Sudan virus (SUDV) and Taï Forest virus (TAFV) spanning outbreaks from 1974 to 2014 in Democratic Republic of Congo (DRC), Uganda, Gabon, Sudan, Ivo...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 231fa301-328e-5fb3-a32a-b5ab954def64
DOI: 10.1101/556910

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Positive selection in the Ebola virus proteomeDOI 10.1101/556910Read

Amino acid mutations in Ebola virus glycoprotein of the 2014 epidemic.Semantic proximity Read

A computational overview on phylogenetic characterization, pathogenic mutations, and drug targets for Ebola virus disease.Semantic proximity Read

Functional Characterization of Adaptive Mutations during the West African Ebola Virus Outbreak.Semantic proximity Read

Comparative Time–Space Evolution of Bundibugyo Ebolavirus Glycoprotein Across the 2007, 2012, and 2026 OutbreaksSemantic proximity Read

Molecular characterization of Ebola virus glycoprotein V75A substitution in the 2018-2020 epidemic.Semantic proximity Read

Did a Single Amino Acid Change Make Ebola Virus More Virulent?Semantic proximity Read

Naturally Occurring Single Mutations in Ebola Virus Observably Impact InfectivitySemantic proximity Read

Ebolavirus is evolving but not changing: No evidence for functional change in EBOV from 1976 to the 2014 outbreak.Semantic proximity Read

Intra-host dynamics of Ebola virus during 2014.Semantic proximity Read

Selection profiles in RNA viruses reflect the characteristics of viruses more than individual proteins.Semantic proximity Read

Ebolavirus Evolution: Past and Present.Semantic proximity Read

Expanding the watch list for potential Ebola virus antibody escape mutationsSemantic proximity Read