Article
A computational overview on phylogenetic characterization, pathogenic mutations, and drug targets for Ebola virus disease.
Current opinion in pharmacology - 1 Dec 2021
Vasudevan Karthick, Thirumal Kumar D, Udhaya Kumar S, Saleem Aisha, Nagasundaram N, Siva R, Tayubi Iftikhar Aslam, George Priya Doss C, Zayed Hatem
Abstract excerpt
The World Health Organization declared Ebola virus disease (EVD) as the major outbreak in the 20th century. EVD was first identified in 1976 in South Sudan and the Democratic Republic of the Congo. EVD was transmitted from infected fruit bats to humans via contact with infected animal body fluids. The Ebola virus (EBOV) has a genome size of ∼18,959 bp. It encodes seven distinct proteins: nucleoprotein (NP),...
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