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Article

Did a Single Amino Acid Change Make Ebola Virus More Virulent?

Cell - 3 Nov 2016

Bedford Trevor, Malik Harmit S

Abstract excerpt

A mutation in the Ebola virus glycoprotein arose early during the 2013-2016 epidemic and dominated the viral population. Two studies by Diehl et al. and Urbanowicz et al. now reveal that this mutation is associated with higher infectivity to human cells, representing the clearest example of Ebola's functional adaptation to human hosts.

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Identifiers

PMID: 27814518
DOI: 10.1016/j.cell.2016.10.032

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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