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Annexin A2 Mediates Bevacizumab Resistance and Infiltrative Escape in Glioblastoma

2026-06-28

Abstract excerpt

<title>Abstract</title> <p>Purpose The clinical benefit of bevacizumab (Bev) in glioblastoma (GBM) is typically transient, as tumors develop adaptive resistance characterized by an infiltrative shift from angiogenesis dependent growth. This study investigated Annexin A2 (ANXA2), a regulator of both angiogenesis and invasion, as a potential mediator of Bev resistance. Methods We analyzed 66 tissue-specimens from...

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Literature Corpus work
23179b3c-e550-51cd-b625-20fede853e7d
DOI
10.21203/rs.3.rs-10073018/v1
Open publication

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Annexin A2 Mediates Bevacizumab Resistance and Infiltrative Escape in GlioblastomaDOI 10.21203/rs.3.rs-10073018/v1
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