Article

Mechanism of SOX9 nuclear translocation induced by NF1 mutation promoting neurofibroma proliferation and collagen secretion

2023-05-31

Abstract excerpt

<title>Abstract</title> Neurofibromatosis type 1 (NF1) is caused by <italic>NF1</italic> gene mutations. Patients with NF1 often have complications with tumors, such as neurofibroma. In order to investigate the pathogenesis of human neurofibroma, a systematic comparison of protein expression levels between Schwann cell-like sNF96.2 cells, originating from malignant peripheral nerve sheath tumors (MPNST), and n...

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Literature Corpus work: 23136926-2e50-5205-881c-c59fc399728a
DOI: 10.21203/rs.3.rs-2974925/v1

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