Article
SOX9 Promotes Collagen VI Secretion by Upregulating PCOLCE in Neurofibroma.
Molecular neurobiology - 1 Oct 2024
Yao Xuan, Wang Bo, Su Yuanping, Bing Zhitong, Li Qiao, Dong Qiang, Yin Hang, Wang Jianying, Pan Yawen, Yuan Guoqiang
Abstract excerpt
Neurofibromatosis type 1 (NF1) is caused by NF1 gene mutations. Patients with NF1 often have complications with tumors, such as neurofibroma. In order to investigate the pathogenesis of human neurofibroma, a systematic comparison of protein expression levels between Schwann cell-like sNF96.2 cells, which originated from malignant peripheral nerve sheath tumors (MPNST), and normal Schwann cells was performed using...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.