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The Effect of the Classical TSPO Ligand PK 11195 On in Vitro Cobalt Chloride Model of Hypoxia in Non-Neuronal and Brain Cell Lines

2021-12-01

Abstract excerpt

The mitochondrial translocator protein (TSPO) is a modulator of the apoptotic pathway involving reactive oxygen species (ROS) generation, mitochondrial membrane potential (Δψm) collapse, activation of caspases and eventually initiation of the apoptotic process. In this in vitro study, H1299 lung cells and BV-2 microglial cells were exposed to the hypoxic effect of CoCl 2 with or without PK 11195. Exposing the H129...

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Literature Corpus work
230b2e6d-90d8-5f66-abb9-19da29ed54a1
DOI
10.21203/rs.3.rs-1101631/v1
Open publication

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The Effect of the Classical TSPO Ligand PK 11195 On in Vitro Cobalt Chloride Model of Hypoxia in Non-Neuronal and Brain Cell LinesDOI 10.21203/rs.3.rs-1101631/v1
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