Article

Evolution of Hominin Polyunsaturated Fatty Acid Metabolism: From Africa to the New World

2017-08-10

Abstract excerpt

<h4>Background</h4> The metabolic conversion of dietary omega-3 and omega-6 18 carbon (18C) to long chain (> 20 carbon) polyunsaturated fatty acids (LC-PUFAs) is vital for human life. Fatty acid desaturase ( FADS ) 1 and 2 catalyze the rate-limiting steps in the biosynthesis of LC-PUFAs. The FADS region contains two haplotypes; ancestral and derived, where the derived haplotypes are associated with more efficie...

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Literature Corpus work: 22b4d736-0ace-586c-bfa8-5b093e9f50c6
DOI: 10.1101/175067

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