Article

Platelet Toll-like Receptor 4-related Innate Immunity Potentially Participates in Transfusion Reactions Independent of ABO Compatibility: An ex Vivo Study

2021-08-04

Abstract excerpt

<h4>Purpose: </h4> The role of platelet TLR4 in transfusion reactions remains unclear. This study analyzed platelet TLR4, certain DAMPs, and the effect of ABO compatibility on TLR4 expression after a simulated transfusion ex vivo . <h4>Methods: </h4>: Donor red blood cells were harvested from a blood bank. Recipient blood from patients undergoing cardiac surgery was processed to generate a washed platelet suspensi...

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Literature Corpus work: 22664065-9c1a-537e-8adc-d7aaae4094a6
DOI: 10.21203/rs.3.rs-762879/v1

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