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Comprehensive circRNA Expression Profile and Transcriptomics-Based Molecular Pathway Analysis of the Sodium-Glucose Co-Transporter-2 Inhibitor Dapagliflozin in Diabetic Tubular Epithelial Cells

2021-08-03

Abstract excerpt

Diabetic kidney disease (DKD) is a serious diabetes complication. Sodium-glucose cotransporter 2 inhibitors (SGLT2i) are novel anti-diabetes drugs and have clinical renal protection. However, the molecular mechanisms involved remain unclear. Here, human proximal tubular epithelial cells (PTECs) were treated with normal glucose (NG), high glucose (HG), and three types of anti-diabetes agents including SGLT2i (dapag...

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Literature Corpus work
a58a1ef6-bf71-5ce1-ac6e-3a83bbd8403e
DOI
10.21203/rs.3.rs-763466/v1
Open publication

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Comprehensive circRNA Expression Profile and Transcriptomics-Based Molecular Pathway Analysis of the Sodium-Glucose Co-Transporter-2 Inhibitor Dapagliflozin in Diabetic Tubular Epithelial CellsDOI 10.21203/rs.3.rs-763466/v1
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