Article

NMR-based Urinary Biomarkers in Pediatric Primary Mitochondrial Disorders and Chronic Kidney Disease: Shared Mitochondrial Dysfunction, Diverging Biosignatures

2025-08-28

Abstract excerpt

<title>Abstract</title> <p> <bold>Background:</bold> Renal involvement is a frequent manifestation of primary mitochondrial disorders (PMD), either as a presenting feature or during the disease course. Simultaneously, the metabolomic profile of chronic kidney disease (CKD) is often associated with underlying mitochondrial dysfunction. This study aimed to characterize urinary metabolic signatures in genetically...

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Literature Corpus work: a1389ecf-71a2-5c3e-a1a7-2988c122df73
DOI: 10.21203/rs.3.rs-6758787/v2

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