Article

Single-cell transcriptomic integrated with machine learning reveals retinal cell-specific biomarkers in diabetic retinopathy

2025-06-07

Abstract excerpt

Diabetic retinopathy (DR) remains a principal cause of vision impairment worldwide, involved complex retinal cellular pathophysiology that remains incompletely understood. To elucidate cell-type-specific molecular signatures underlying DR, we generated a high-resolution single-cell transcriptomic atlas of 297,121 retinal cells from 20 Chinese donors, including non-diabetic controls (26.4%), diabetic without retino...

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Literature Corpus work: 2201581d-8f16-58f9-ad59-1086bac4462e
DOI: 10.1101/2025.06.03.657753

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