Article

Mutational Profile Enables the Identification of a High Risk Subgroup in Myelodysplastic Syndromes With Isolated Trisomy 8

2023-02-01

Abstract excerpt

<title>Abstract</title> <p>Trisomy 8 (+ 8) is the most frequent trisomy in myelodysplastic syndromes (MDS) and is associated to clinical heterogeneity and intermediate cytogenetic risk when found isolated. The presence of gene mutations in this group of patients and the prognostic significance has not been extensively analyzed. Targeted-deep sequencing was performed in a cohort of 79 MDS patients showing isolated...

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Literature Corpus work: 21f8847c-c656-5c9a-8530-ccdb2286272c
DOI: 10.21203/rs.3.rs-2524683/v1

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