Article

Sofosbuvir-Upregulated Genes Facilitate The Development of Hepatocellular Carcinoma

2020-12-22

Abstract excerpt

<title>Abstract</title> <p><bold>Background: </bold>Direct-acting antivirals (DAAs) have achieved a sustained virological response (SVR) rate of 95-99% in treating HCV. Several studies suggested that treatment with sofosbuvir (SOF) containing DAAs may be associated with increased risk of developing HCC. The aim of this study is to investigate the potential mechanisms of SOF on the development of HCC.<bold>Methods...

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Literature Corpus work: 21f1cfcf-76ab-5ddd-b1ed-36cf695b5e34
DOI: 10.21203/rs.3.rs-130882/v1

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