Article

Preliminary transcriptome profiling reveals RUFY1, ABCC3 and DNAJC7 genes are significantly dysregulated among hepatitis B virus-induced hepatocellular carcinoma patients in Nigeria.

2025-07-09

Abstract excerpt

<title>Abstract</title> <p>Chronic hepatitis B (CHB) infection affects about 20 million Nigerians and its most fatal complication is hepatocellular carcinoma (HCC) which lacks sensitive and specific diagnostic markers for detection at a very early stage. Consequently, this study assessed dysregulated genes across the clinical spectrum of HBV infection as potential non-invasive biomarkers of early-stage HCC. The t...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: e9d2af05-7cdb-5f82-82eb-75062719a636
DOI: 10.21203/rs.3.rs-7055265/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Preliminary transcriptome profiling reveals RUFY1, ABCC3 and DNAJC7 genes are significantly dysregulated among hepatitis B virus-induced hepatocellular carcinoma patients in Nigeria.DOI 10.21203/rs.3.rs-7055265/v1Read

Molecular Prognostic Profile of Egyptian HCC Cases Infected with Hepatitis C VirusSemantic proximity Read

Bioinformatic Identification and Validation of Key Genes and Biological Pathways Involved in Hepatitis B Virus-related Hepatocellular CarcinomaSemantic proximity Read

Comparative transcriptome analysis of peripheral blood mononuclear cells in hepatitis B-related acute-on-chronic liver failureSemantic proximity Read

Identification of long noncoding RNAs biomarkers in patients with hepatitis B virus-associated hepatocellular carcinomaSemantic proximity Read

RNA-Seq profiling revealed PBMC RNA as potential biomarker for hepatocellular carcinomaSemantic proximity Read

Comprehensive analysis of long non-coding RNA expression profiles in hepatitis B virus-related hepatocellular carcinomaSemantic proximity Read

Transcriptomic Analysis of Hepatitis B Infected Liver for Prediction of Hepatocellular Carcinoma RiskSemantic proximity Read

RNA-Seq Profiling Revealed PBMC RNA as Potential Biomarker for Hepatocellular CarcinomaSemantic proximity Read

Comprehensive transcriptomic analysis of hepatocellular Carcinoma: Uncovering shared and unique molecular signatures across diverse etiologiesSemantic proximity Read

Analysis of Host Factor Networks during Hepatitis B Virus Infection in Primary Human HepatocytesSemantic proximity Read

A comprehensive comparison of molecular and phenotypic profiles between hepatitis B virus (HBV)-infected and non-HBV-infected hepatocellular carcinoma by multi-omics analysis.Semantic proximity Read

Comparative Analysis of the Mutational Profile in HBV-Related and Non-HBV-Related Hepatocellular CarcinomaSemantic proximity Read