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Article

Clinical significance of long non-coding RNA HOTTIP in early-stage non-small-cell lung cancer

28 Feb 2019

Abstract excerpt

BACKGROUND: HOTTIP, a long non-coding RNA located in the HOXA cluster, plays a role in the patterning of tissues with mesodermal components, including the lung. Overexpression of HOXA genes, including HOTTIP, has been associated with a more aggressive phenotype in several cancers. However, the prognostic impact of HOTTIP has not yet been explored in non-small-cell lung cancer (NSCLC). We have correlated HOTTIP...

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PMID: 30819158
DOI: 10.1186/s12890-019-0816-8

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