Article
Common neurodegeneration-associated proteins are physiologically expressed by antigen-presenting cells and are interconnected via the inflammation/autophagy-related proteins TRAF6 and SQSTM1
2019-07-02
Abstract excerpt
<h4>ABSTRACT</h4> There is circumstantial evidence that, under neurodegenerative conditions, peptides deriving from aggregated or misfolded specific proteins elicit adaptive immune responses. On another hand, several genes involved in familial forms of neurodegenerative diseases were found to exert key innate immune functions. However, whether or not such observations are causally linked remains unknown. To start...
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Identifiers and source
- Literature Corpus work
- 21c00658-edd2-5afb-ae60-12706f5bc34d
- DOI
- 10.1101/690677