Article
Immunological detection of blast cell subpopulations in acute myeloblastic leukemia at diagnosis: implications for minimal residual disease studies.
Leukemia - 1 Jun 1995
Macedo A, Orfão A, Gonzalez M, Vidriales M B, López-Berges M C, Martínez A, San Miguel J F
Abstract excerpt
The aim of the present study was to analyze the incidence of AML cases displaying more than one blast cell subpopulation by immunophenotype at diagnosis, since, any of them, although minimal, can be responsible for the relapse. For this purpose we have prospectively investigated the immunophenotype of blast cells from 40 de novo AML patients at diagnosis with a large panel of monoclonal antibodies in double and...
Topics
- Antigens, CD
- Blast Crisis
- Bone Marrow
- Female
- Flow Cytometry
- Humans
- Immunophenotyping
- Leukemia, Myeloid, Acute
- Male
- Phenotype