Article

Multiomics coupled with vibrational spectroscopy identify early mechanisms of experimental aortic valve stenosis

2024-05-02

Abstract excerpt

<title>Abstract</title> <p>Calcific aortic valve stenosis (CAVS), characterized by calcium deposition in the aortic valve in a multiannual process, is associated with high mortality and morbidity. To understand phenomena at its early stages, reliable animal models are needed. Here, we used a critically revised high-fat vitamin D2 diet rabbit model to unveil the earliest in vivo-derived mechanisms linked to CAVS p...

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Literature Corpus work: 20e173bf-c52f-594f-994c-e3554fb3a9aa
DOI: 10.21203/rs.3.rs-4330270/v1

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