Article

Rapid enzymatic assay for antiretroviral drug monitoring using CRISPR-Cas12a enabled readout

2024-11-28

Abstract excerpt

Maintaining efficacy of human immunodeficiency virus (HIV) medications is challenging among children because of dosing difficulties, the limited number of approved drugs, and low rates of medication adherence. Drug level feedback (DLF) can support dose optimization and timely interventions to prevent treatment failure, but current tests are heavily instrumented and centralized. We developed the REverse-transcripta...

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Identifiers and source

Literature Corpus work: 20c11d80-eea0-5b65-ba30-f64a5c522635
DOI: 10.1101/2024.11.25.625292

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