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High expression of COL1A1 exaggerates bone metastasis in estrogen receptor-positive (ER+) breast cancer and is potential to serve as a novel therapeutic target

2022-05-09

Abstract excerpt

Bone metastasis accounts for a frequent complication in advanced estrogen receptor-positive (ER+) breast cancer, with staggeringly high percentage up to 70%. However, our understanding of molecular mechanisms underlying bone metastasis remains insufficient. In our study, 216 differentially expressed genes (DEGs) related to bone metastasis in ER + breast cancer were screened out. Enrichment analysis showed that, DE...

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Identifiers and source

Literature Corpus work
20578a76-d31d-5b1e-8e42-572adc1d9deb
DOI
10.21203/rs.3.rs-1614322/v1
Open publication

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High expression of COL1A1 exaggerates bone metastasis in estrogen receptor-positive (ER+) breast cancer and is potential to serve as a novel therapeutic targetDOI 10.21203/rs.3.rs-1614322/v1
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