Article

Assessing 16S marker gene survey data analysis methods using mixtures of human stool sample DNA extracts

2018-08-25

Abstract excerpt

<h4>Background</h4> Analysis of 16S rRNA marker-gene surveys, used to characterize prokaryotic microbial communities, may be performed by numerous bioinformatic pipelines and downstream analysis methods. However, there is limited guidance on how to decide between methods, appropriate data sets and statistics for assessing these methods are needed. We developed a mixture dataset with real data complexity and an ex...

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Literature Corpus work: 20467668-93ff-5836-adda-6411d4fc49a9
DOI: 10.1101/400226

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